Both in-character and equal speed?
- Spot's strongest hax abilities are portal creation/dimensional travel (which acts as BFR and attack reflection, durability negation (cutting through objects), teleportation and genius intelligence. He fought Miles, Mumbattan Spidey, Spider-Punk and Gwen, who are all far superior in strength and abilities compared to the Thunderbolts. He's also got resistance to Matter Manipulation on an atomic level, so Sentry's 'likely MM' won't do that much here.
- Sentry has enhanced senses against nearby activity, martial arts, shockwaves (which is tens of meters), afterimages (good for misleading opponents), telekinesis (he can use this to throw nearby objects, but it'll be useless with his Class 100 LS), heat manipulation and nigh-invulnerability.
1. In character, Spot is rather conservative with his dark matter usage to create portals. Since MCU's Earth doesn't have any colliders (or many sources of dark matter), he'll be held back on using portals. Given his pre-Super Collider personality, he was rather chill with Miles (for instance, let him talk on the phone with his dad), but he didn't seem concerned with damaging Mumbattan, so I wouldn't be surprised if he just leads off with trying to put Sentry in some random universe.
2. In character, Sentry uses telekinesis to reflect attacks back, grapple opponents or freeze them. If that doesn't work, he uses heat manipulation + physical strength. Personality-wise, he doesn't like killing his opponents and goes easy on them; for example, he only had just met Red Guardian and Bucky at the WatchTower, but still didn't listen to Valentina's orders to "finish them off". He is willing to knock people out (like he did to Bucky). I'd say his biggest combat weakness is letting people get their attacks on him, since he's confident in his invincibility (dammit Valentina...)
Sentry has a problem of not using his full power (because he really held back 200 million times lower than his normal AP to fight the Thunderbolts), and even though The Spot doesn't look human, that won't change much. Likewise, The Spot doesn't show the personality of personally wanting to execute people who haven't wronged him; he's just unaware of the damage he causes.
Anyway, The Spot is a lot smarter than Sentry, and was able to force Miles into multiple portals throughout their first fight. Sentry does have awareness-based ES, so he counters oncoming physical attacks, but I don't see him anticipating close-ranged portals.
I'm giving it to
The Spot Extreme-Diff. He can bait Sentry into a random portal to an unknown universe (given his 5-D range), and it'll be so much easier thanks to equal speed. Spot is outmatched in AP but he's significantly smarter, has better win-con hax's (portals, dimensional travel, BFR), attack reflection (to reflect physical strikes) and teleportation (which gives him time to strategize.)
This is a VERY CLOSE match. Great one OP.