this is definitely way more doable for the pubsec duo. given the two's general intelligence, the second they get dropped into the castle they're just going to rely on qingyi's enhanced senses and extrasensory perception to track down and figure out where exactly dimi is. i'm admittedly not sure how dimi will act in character but i think the pubsec duo will definitely try to get the element of surprise to get the jump on her. i guess dimi having prior knowledge of ether corruption is nice but it doesn't save her from the effects of it since she doesn't seem immune to any of them. she also isn't immune to qingyi's electricity manip so qingyi can just play offensively and repeatedly shock her over and over while ZY supports from the sideline and pelts her with bullets. given both of their superior LS' to dimi from the looks of it, it also means they can effectively pin her down to incap her if necessary. i think they'll go more for lethal force here, especially given A. the prior knowledge that she isn't human, B. the fact that they'll likely be able to see her regenerate from lethal wounds and C. the second she transforms and starts turning into that weird bug monster or whatever i think they'd pretty obviously deem her a threat
i'm not really sure how the daughters play a role into her fighting style (again i don't RE) but from the looks of it it does just seem like qingyi can act as the main offensive fighter while ZY harasses from the sidelines. zhu yuan still has vital view here to avoid taking lethal hits, and she can probably also leverage it to help get qingyi out of danger in the event she gets into a dangerous position
definitely seems like a pretty concrete W for the pubsec duo imo. they can definitely just stall long enough for her to get incapped by ether corruption. although again, i don't RE, so i'm not really super knowledgeable on what dimi can do