Yes. But. One way to get around it entirely is for a person to charge at Accelerator, punch him and simply pull back at the last second for Accelerator's vector shield to propel said fist towards Accelerator and hit him instead of reflecting it. Mind you, this is a "special move" that only a martial artist that knows Accelerator's power to a T could perform... safely.
A random assassin w/o much notable skill nor not much knowhow about Accelerator's power, 'sides knowing the trick itself existed, could do it. Albeit some damage was reflected back at his hand but he could continue fighting just find, IIRC.
All of these peps are random, mundane martial artist-and Reid is a skill god among skill gods in Re:Zero with instincts and combat knowhow, he could probably pull it off. Even in the worst case, he can still bypass Accelerator's barrier to land a single hit and Accelerator gets utterly wiped via sheer AP difference.
Would probably try to engage in CQC, but he would likely won't be able to touch Reid through due to his sheer skill. And all of his dura-neg moves are touch-based, i.e, his blood reversal trick requires him to dig his fingers inside a person's wound to actually perform it.
From here, Reid simply needs to wait out Accelerator for 30mins until his power runs out and he turns into back into a cripple w/o power OR he just needs to force Accelerator unground/bury him in enough rubble to block his choker from getting a signal to disable him entirely that way as per the latest volume of ToAru.