First things first, Namekians are confirmed to be from the Demon Realm, which ties in to the whole "Demon King Piccolo" thing and allat, an idea that kinda got dropped until now. The Namekian's being from a different realm was teased in the Granolah Arc so that means this concept HAS been in the works for years now at bare minimum. Apparently there was a line of Demon King's/Supreme Demon King's with Dabura being the last before the new guy. And Dabura had a father named Abura.
Cosmology upgrades might go hard here. It is confirmed that there are in fact 3 different Demon Worlds within the Demon Realm, which in itself is separated from the "Outside World", wherein all of main Dragon Ball takes place, including the 12 universes as a whole. Considering the implications we get, we're probably talking about different space-times as well. This could be interpreted as a good Zeno statement given that Whis should very much be aware of the Demon Realm. Additionally, there is some kind of gateway guardian that controls the travel between different realms and worlds. I hope we get more context on these things. Oh and it was said that Babidi intended to use Buu to rule over not just the main world, but ALL worlds, including the Demon Realm. So Buu was really built different back in those days. Besides Beerus he was def the strongest individual entity in Universe 7 in his reign.
The Demon Realm has its own set of Dragon Ball's, created by the ancient Namekian Neva who likely predates the Namekian's of the Outside World and hasn't seen another of his kind in thousands of years, with this set likely divided between the 3 different Demon World's, but hasn't been confirmed. These Dragon Balls are individually protected by seemingly mechanical beings who are so powerful that apparently no one has collected the set in an extremely long time. This could imply that Dabura was inferior to these guardians depending on interpretation, which means we could be talking about SSJ2 Buu Saga caliber characters, but they're probably stronger than that. Neva also has the ability to detect and summon Dragon Ball's, though it's apparently harder when they are inactive. Just my gut but I'm feeling like Neva will somehow tie into Zalama later in Daima. He might have even directly interacted with him. It's being implied that Neva might be the originator of the Namekian form of the Dragon Ball's which are in turn a knock-off of the Super Dragon Ball's. This ties in with the size thing. Super Dragon Ball's being the largest by literal astronomical difference, then the Demon Realm Dragon Ball's, then the Namekian Dragon Ball's, then Earth, then the ones on Granolah's planet. I might be forgetting some of the lore though but it adds up.
Apparently, there are different classes of magic, with Shenron's magic being "white magic", the implication being that white and black magics differ from morality, so Shenron cannot do any directly evil things through wishes. Interestingly, this might retcon the old concept that Shenron couldn't kill anyone stronger than Kami, as they only imply he can't do it because it's outside of the category of magic he uses.
Supreme Kai has multiple siblings so that's something.
Confirmed to be taking place within a year after the Buu Saga due to Trunks celebrating his 9th birthday.
In Daima, Kibitoshin got unfused by Buu using his "magical gases" which was the original explanation for Vegito in the Buu Saga. It's obvious that this is a plot device because the show needs Shin for a plotline, but nevertheless the implications are kinda big. This also probably ties in to Buu's magical resistances in the Moro arc.
Also Supreme Kai having evil siblings is REALLY interesting and there may be more to Kai's than we thought if they can just branch off and do their own thing.