Then it starts the out of character fallacy, nothing new here
Dante's fight are mostly in gameplay and while the anime does show his fights from a "cutscene" persperctive, Dante never, besides Sid, fough someone remotely near his level in the anime, so saying that he doesn't used basing on that and out-of-battle cutscenes is just wrong by default. Against Sid, when Dante attacked him at the top, he went DT, one shot the poor guy and call it a day, didn't even need hax at all
So what you think Dante is going to let Itachi corner him with Susanoo and not use his powers to overcome him ? Itachi's weapons relies on Mind Hax, which get resisted, that "nervous system" thing will not allow Itachi to just overcome said resistance, it's not even listed on the
Mind Manipulation, so I'll not take into acount, there is also the fact that Itachi uses the opponent's Chakra to do it each, well, Dante doesn't have
Totsuka needs to stab Dante to work, not going to happen that easy since even Base Dante can block with Royalguard, each is capable of blocking attacks capable of one shoting Dante and also Power Nulls the attack. Add that to Time Slow, Time Stop, Deconstruction, Teleportation and Soul Hax, and Itachi doesn't win here
Also, Dante can destroy souls capable of resisting the Demon World Soul Hax ehile they ae inside the opponent, destroying the soul by hitting the target is Soul Hax